KEGG   Homo sapiens (human): 1103
Entry
1103              CDS       T01001                                 
Symbol
CHAT, CHOACTASE, CMS1A, CMS1A2, CMS6
Name
(RefSeq) choline O-acetyltransferase
  KO
K00623  choline O-acetyltransferase [EC:2.3.1.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00564  Glycerophospholipid metabolism
hsa04725  Cholinergic synapse
Disease
H00770  Congenital myasthenic syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    1103 (CHAT)
 09150 Organismal Systems
  09156 Nervous system
   04725 Cholinergic synapse
    1103 (CHAT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.6  choline O-acetyltransferase
     1103 (CHAT)
SSDB
Motif
Pfam: Carn_acyltransf
Other DBs
NCBI-GeneID: 1103
NCBI-ProteinID: NP_065574
OMIM: 118490
HGNC: 1912
Ensembl: ENSG00000070748
UniProt: P28329
Structure
Position
10:49609095..49667942
AA seq 748 aa
MGLRTAKKRGLGGGGKWKREEGGGTRGRREVRPACFLQSGGRGDPGDVGGPAGNPGCSPH
PRAATRPPPLPAHTPAHTPEWCGAASAEAAEPRRAGPHLCIPAPGLTKTPILEKVPRKMA
AKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQ
QKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLIS
GVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPE
PEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSE
WAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGANR
WYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHVTQSSRKLIRADSVSELPAP
RRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQ
LAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLL
KDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTSQV
PTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDMRD
LCSLLPPTESKPLATKEKATRPSQGHQP
NT seq 2247 nt   +upstreamnt  +downstreamnt
atggggctgaggacagcgaagaagagggggcttgggggaggggggaaatggaagagagag
gagggaggaggtacaagaggaaggagagaagtgcggccagcttgctttctccagtcgggt
ggccgcggggacccgggcgacgtcggaggccctgccgggaacccaggctgcagcccccac
ccccgcgctgcgacacgccccccaccccttccggctcacacccccgcccacactcctgag
tggtgcggtgcagcgtcggccgaggcagcagagccgaggagagcaggtccacacctctgc
atccctgcaccaggactcaccaagacgcccatcctggaaaaggtcccccgtaagatggca
gcaaaaactcccagcagtgaggagtctgggctgcccaaactgcccgtgcccccgctgcag
cagaccctggccacgtacctgcagtgcatgcgacacttggtgtctgaggagcagttcagg
aagagccaggccattgtgcagcagtttggggcccctggtggcctcggcgagaccctgcag
cagaaactcctggagcggcaggagaagacagccaactgggtgtctgagtactggctgaat
gacatgtatctcaacaaccgcctggccctgcctgtcaactccagccctgccgtgatcttt
gctcggcagcacttccctggcaccgatgaccagctgaggtttgcagccagcctcatctct
ggtgtactcagctacaaggccctgctggacagccactccattcccactgactgtgccaaa
ggccagctgtcagggcagcccctttgcatgaagcaatactatgggctcttctcctcctac
cggctccccggccatacccaggacacgctggtggctcagaacagcagcatcatgccggag
cctgagcacgtcatcgtagcctgctgcaatcagttctttgtcttggatgttgtcattaat
ttccgccgtctcagtgagggggatctgttcactcagttgagaaagatagtcaaaatggct
tccaacgaggacgagcgtttgcctccaattggcctgctgacgtctgacgggaggagcgag
tgggccgaggccaggacggtcctcgtgaaagactccaccaaccgggactcgctggacatg
attgagcgctgcatctgccttgtatgcctggacgcgccaggaggcgtggagctcagcgac
acccacagggcactccagctccttcacggcggaggctacagcaagaacggggccaatcgc
tggtacgacaagtccctgcagtttgtggtgggccgagacggcacctgcggtgtggtgtgc
gaacactccccattcgatggcatcgtcctggtgcagtgcactgagcatctgctcaagcac
gtgacgcagagcagcaggaagctgatccgagcagactccgtcagcgagctccccgccccc
cggaggctgcggtggaaatgctccccggaaattcaaggccacttagcctcctcggcagaa
aaacttcaacgaatagtaaagaaccttgacttcattgtctataagtttgacaactatggg
aaaacattcattaagaagcagaaatgcagccctgatgccttcatccaggtggccctccag
ctggccttctacaggctccatcgaagactggtgcccacctacgagagcgcgtccatccgc
cgattccaggagggacgcgtggacaacatcagatcggccactccagaggcactggctttt
gtgagagccgtgactgaccacaaggctgctgtgccagcttctgagaagcttctgctcctg
aaggatgccatccgtgcccagactgcatacacagtcatggccataacagggatggccatt
gacaaccacctgctggcactgcgggagctggcccgggccatgtgcaaggagctgcccgag
atgttcatggatgaaacctacctgatgagcaaccggtttgtcctctccactagccaggtg
cccacaaccacggagatgttctgctgctatggtcctgtggtcccaaatgggtatggtgcc
tgctacaacccccagccagagaccatccttttctgcatctctagctttcacagctgcaaa
gagacttcttctagcaagtttgcaaaagctgtggaagaaagcctcattgacatgagagac
ctctgcagtctgctgccgcctactgagagcaagccattggcaacaaaggaaaaagccacg
aggcccagccagggacaccaaccttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (35)   
   KEGG ORTHOLOGY (1)   
   RefGene (29)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (31)   
   RefSeq(nuc) (7)   
   GenBank (12)   
   EMBL (12)   
3D Structure (5)   
   PDB (5)   
Protein domain (1)   
   Pfam (1)   
All databases (95)   

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